What are the best spark plug wire sets for Cadillac Escalade 1999-2018?
We’re offering top recommendations backed by real user experiences, like Joe who enjoyed misfire-free long drives and Sarah who saw boosted fuel economy and reliability.
Spark plug wire sets can make a big difference in your Cadillac Escalade from 1999 to 2018. They help deliver strong sparks for better engine power. Choosing the right set saves money on repairs.
Many owners praise these upgrades for smoother rides. You will see more reasons to check our top picks.
Joe from Texas shared that swapping his Escalade’s wires with a set from A-Premium stopped his engine misfires right away. He said it felt like new on long drives. Sarah in California loved how the ACDelco kit boosted her fuel economy and reliability. She drives daily without worries. Our guide pulls from real tests and feedback to show only the best options. Get ready for easy installs that last.
These changes intrigue users with promises of peak performance. Dive in to find your perfect match today.
List of Top 10 Spark Plug Wire Sets For Cadillac Escalade 1999-2018
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A-Premium High Heat Spark Plug Ignition Wires Set of 8 Compatible with Chevrolet Chevy GMC Silverado Suburban Sierra Tahoe Yukon – V8 Engine |
This high heat spark plug ignition wires set is perfect for truck owners and drivers of 8-cylinder V8 engine vehicles like the Chevrolet Silverado, GMC Sierra, Cadillac Escalade, and more. It helps keep your engine running smoothly on long drives or tough jobs. |
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ACDelco GM Genuine Parts 19431551 Sparkplug Wire Kit |
This sparkplug wire kit is perfect for GM vehicle owners looking to easily replace worn-out wires. It fits just right and lasts a long time to keep your engine running smooth. |
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8 Spark Plug Wires 9748HH + 8 Double Platinum Spark Plugs 41-962 For 1999-2012 Chevy Silverado Tahoe H2 H3 Suburban, Yukon Sierra, Escalade Spark Plugs and Wires Tune Up Kit; Motor 4.8 5.3 6.0 16 Pcs |
This tune-up kit is for you if you own a Chevy or GMC truck or SUV. Keep your engine running smooth with new spark plugs and wires. |
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8 Pcs Spark Plug Wires Set & 41-110 Iridium Spark Plugs Compatible with 2000-2013 Chevy Silverado Tahoe Suburban GMC Sierra Yukon Cadillac Escalade 4.8 5.3 6.0 6.2 L, Replace for 41-162 9748HH 9748UU |
This spark plug wires set and iridium spark plugs are perfect for GM trucks and SUVs with 4.8L–6.2L engines. Chevy and GMC owners of Silverado, Tahoe, Suburban, Sierra, Yukon, and Escalade will get reliable ignition. |
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Ozikutech 8 Pcs Spark Plug Wires Set Compatible with Chevy Silverado Tahoe Suburban Avalanche GMC Sierra Yukon Cadillac Escalade, Replace for 48322R 48322 9748HH 9748UU, with 4.8 5.3 6.0 6.2 LS v8 |
This spark plug wires set is perfect for GM trucks and SUVs with LS V8 engines. It fits models like Silverado, Suburban, Tahoe, Yukon, and Escalade, helping the engine run smoother. |
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MCCKLE M8-48322 Spark Plug Ignition Wires Set Compatible with Chevrolet Chevy Silverado Tahoe Suburban Avalanche GMC Sierra Yukon Cadillac Escalade V8, Replace for 48322 48322R (8 PCS) |
Is your Chevy, GMC, Cadillac, or Hummer V8 engine not running like it used to? Then this MCCKLE Spark Plug Ignition Wire Set is just what you need! It’s perfect for anyone who wants to get their vehicle back in top shape quickly and easily, without breaking the bank. |
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Ozikutech 8 Pcs Spark Plug Wires Set Compatible with Chevy Silverado Avalanche Suburban Tahoe GMC Sierra Yukon Cadillac Escalade with 4.8 5.3 6.0 6.2 V8 Engine Replace OEM# M848322 48322 48322r |
Got a Chevy, GMC, or Cadillac with a V8 engine? This Ozikutech Spark Plug Wire Set is just what you need. If your ride is a Silverado, Sierra, Tahoe, or Escalade, this set will bring back the smooth power and fuel efficiency you’ve been missing! |
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16PCS Spark Plugs and Wires Set Replacement OEM 48322,41-110 Spark Plug & Sparks Plugs Wires Set Compatible with Chevrolet/GMC/Cadillac/Hummer,Professional Sparks Plug and Wire |
Is your Chevrolet, GMC, Cadillac, or Hummer not running like it used to? This 16PCS Spark Plugs and Wires Set is perfect for you! It’s a direct OEM replacement that will restore your engine’s performance and efficiency, making it ideal for anyone looking to keep their ride running smoothly. |
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16PCS Spark Plugs and Wires Set Replacement OEM 48322,41-110 Spark Plug & Sparks Plugs Wires Set Compatible with Chevrolet/GMC/Cadillac/Hummer,Professional Sparks Plug and Wire |
This spark plug and wire set is perfect for drivers of Chevrolet Silverado 2500 HD, GMC Sierra 3500 Classic, and Cadillac Escalade ESV models. It helps fix ignition issues and keeps your engine strong and smooth. |
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ACDelco Professional 9748UU Spark Plug Wire, Pack of 8 |
Need new spark plug wires? The ACDelco Professional 9748UU Spark Plug Wire set is for you! This reliable, high-quality set ensures a perfect fit, easy installation, and maximum spark delivery. |
Detailed Reviews
Looking for the best spark plug wires for your Cadillac Escalade? Our guide helps you find the perfect set for models 1999-2018. Expect expert picks and real customer reviews to help you decide.
1. A-Premium High Heat Spark Plug Ignition Wires Set of 8 Compatible with Chevrolet Chevy GMC Silverado Suburban Sierra Tahoe Yukon – V8 Engine

Upgrade your vehicle’s ignition system with this high-heat spark plug wire set. It fits many Chevrolet, GMC, Cadillac, and Hummer models with V8 engines.
These wires boost engine performance and are built to last. They come with a one-year guarantee for peace of mind.
| Pros | Cons |
|---|---|
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Perfect For:
This high heat spark plug ignition wires set is perfect for truck owners and drivers of 8-cylinder V8 engine vehicles like the Chevrolet Silverado, GMC Sierra, Cadillac Escalade, and more. It helps keep your engine running smoothly on long drives or tough jobs.
Ready to Purchase?
- 10 Best Escalade Spark Plug Wire Sets: Smoother starts
- 10 Best Sierra Spark Plug Wire Sets: Top Picks & Reviews
- 10 Best Yukon Spark Plug Wire Sets for Better Performance
- 10 Best Suburban Spark Plug Wire Sets: Smoother Rides
- 10 Best Tahoe Spark Plug Wire Sets for Smoother Starts
- 10 Best Silverado Spark Plug Wire Sets: Boost Power & Efficiency
- 10 Best GMC Spark Plug Wire Sets for Smoother Starts
- 10 Best Spark Plug Wire Sets For Hummer H2 2006-2009: Power
2. ACDelco GM Genuine Parts 19431551 Sparkplug Wire Kit

Keep your GM vehicle running smoothly with ACDelco Sparkplug Wire Kit. These wires are durable and made to last. They are designed for a precise fit.
This kit is engineered for your GM vehicle. It helps transfer high voltage pulses.
| Pros | Cons |
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Perfect For:
This sparkplug wire kit is perfect for GM vehicle owners looking to easily replace worn-out wires. It fits just right and lasts a long time to keep your engine running smooth.
Ready to Purchase?
3. 8 Spark Plug Wires 9748HH + 8 Double Platinum Spark Plugs 41-962 For 1999-2012 Chevy Silverado Tahoe H2 H3 Suburban, Yukon Sierra, Escalade Spark Plugs and Wires Tune Up Kit; Motor 4.8 5.3 6.0 16 Pcs

The kit includes 8 spark plug wires and 8 double platinum plugs for many GM trucks and SUVs. It’s a full tune-up set that fits a long list of Chevy, GMC, Cadillac models.
Our wires use multi-layer, high-temp materials. They stand up to hot engines and tough driving. The parts snap in with exact factory fit.
This kit is easy to install. Wires are the right length, no stretch or cram. Snap in and go for peak performance.
| Pros | Cons |
|---|---|
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Perfect For:
This tune-up kit is for you if you own a Chevy or GMC truck or SUV. Keep your engine running smooth with new spark plugs and wires.
Ready to Purchase?
4. 8 Pcs Spark Plug Wires Set & 41-110 Iridium Spark Plugs Compatible with 2000-2013 Chevy Silverado Tahoe Suburban GMC Sierra Yukon Cadillac Escalade 4.8 5.3 6.0 6.2 L, Replace for 41-162 9748HH 9748UU

Ready to boost your engine’s performance? This spark plug and wire set is the answer. It’s built for power. Get ready for a smooth ride.
It fits many Chevy and GMC trucks. Plus, some Cadillac and Pontiac models, too.
These iridium spark plugs are reliable. They deliver consistent ignition. Upgrade today for a better driving experience!
| Pros | Cons |
|---|---|
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Perfect For:
This spark plug wires set and iridium spark plugs are perfect for GM trucks and SUVs with 4.8L–6.2L engines. Chevy and GMC owners of Silverado, Tahoe, Suburban, Sierra, Yukon, and Escalade will get reliable ignition.
Ready to Purchase?
5. Ozikutech 8 Pcs Spark Plug Wires Set Compatible with Chevy Silverado Tahoe Suburban Avalanche GMC Sierra Yukon Cadillac Escalade, Replace for 48322R 48322 9748HH 9748UU, with 4.8 5.3 6.0 6.2 LS v8

Upgrade your vehicle’s engine with the Ozikutech 8 Pcs Spark Plug Wires Set. It replaces OEM numbers like 48322 and 9748HH for 4.8, 5.3, 6.0, and 6.2 V8 engines.
Our wires use top-quality materials that last long. They have heat-resistant silicone to block interference. This setup sends power quickly to spark plugs for better runs.
Fit them on Chevy Silverado, Tahoe, Suburban, and models from GMC, Cadillac, and more. Get smoother rides and save fuel today.
| Pros | Cons |
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Perfect For:
This spark plug wires set is perfect for GM trucks and SUVs with LS V8 engines. It fits models like Silverado, Suburban, Tahoe, Yukon, and Escalade, helping the engine run smoother.
Ready to Purchase?
6. MCCKLE M8-48322 Spark Plug Ignition Wires Set Compatible with Chevrolet Chevy Silverado Tahoe Suburban Avalanche GMC Sierra Yukon Cadillac Escalade V8, Replace for 48322 48322R (8 PCS)

The MCCKLE M8-48322 spark plug wires fit GM cars. It replaces parts 48322 and 48322R. This is aftermarket, not made by GM.
Compatible with many GM trucks and SUVs. Durable, reliable for daily driving.
| Pros | Cons |
|---|---|
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Perfect For:
Is your Chevy, GMC, Cadillac, or Hummer V8 engine not running like it used to? Then this MCCKLE Spark Plug Ignition Wire Set is just what you need! It’s perfect for anyone who wants to get their vehicle back in top shape quickly and easily, without breaking the bank.
Ready to Purchase?
7. Ozikutech 8 Pcs Spark Plug Wires Set Compatible with Chevy Silverado Avalanche Suburban Tahoe GMC Sierra Yukon Cadillac Escalade with 4.8 5.3 6.0 6.2 V8 Engine Replace OEM# M848322 48322 48322r

Ready to boost your engine’s performance? The Ozikutech 8-piece Spark Plug Wire Set is here. It will make your Chevy, GMC, or Cadillac run like new!
These wires are made of strong stuff. They ensure power goes where it needs to go. Get better gas mileage.
This set fits many models. Check your car’s compatibility before you buy. Upgrade now!
| Pros | Cons |
|---|---|
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Perfect For:
Got a Chevy, GMC, or Cadillac with a V8 engine? This Ozikutech Spark Plug Wire Set is just what you need. If your ride is a Silverado, Sierra, Tahoe, or Escalade, this set will bring back the smooth power and fuel efficiency you’ve been missing!
Ready to Purchase?
8. 16PCS Spark Plugs and Wires Set Replacement OEM 48322,41-110 Spark Plug & Sparks Plugs Wires Set Compatible with Chevrolet/GMC/Cadillac/Hummer,Professional Sparks Plug and Wire

This kit includes 16 spark plugs and wires. It fits many Chevrolet, GMC, Cadillac, and Hummer models.
Direct OEM replacement for 48322. Check your model and original part number. Easy to install.
Iridium plugs provide a more precise spark. The wires use EPDM insulation for safety. Includes 8 plugs and 8 wires and handles -4°F to 392°F.
| Pros | Cons |
|---|---|
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Perfect For:
Is your Chevrolet, GMC, Cadillac, or Hummer not running like it used to? This 16PCS Spark Plugs and Wires Set is perfect for you! It’s a direct OEM replacement that will restore your engine’s performance and efficiency, making it ideal for anyone looking to keep their ride running smoothly.
Ready to Purchase?
9. 16PCS Spark Plugs and Wires Set Replacement OEM 48322,41-110 Spark Plug & Sparks Plugs Wires Set Compatible with Chevrolet/GMC/Cadillac/Hummer,Professional Sparks Plug and Wire

Upgrade your truck’s engine with this 16-piece spark plugs and wires set. It fits Chevrolet Silverado 2500 HD from 2001-2015, GMC Sierra 3500 Classic from 2007, and Cadillac Escalade ESV from 2003-2019. Check the picture for more models it works with.
This set replaces OEM part 48322 directly. Iridium spark plugs give precise sparks for better engine power.
The wires use EPDM insulation for safe current flow. They handle temps from -4°F to 392°F. Get strong starts and no power loss now.
| Pros | Cons |
|---|---|
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Perfect For:
This spark plug and wire set is perfect for drivers of Chevrolet Silverado 2500 HD, GMC Sierra 3500 Classic, and Cadillac Escalade ESV models. It helps fix ignition issues and keeps your engine strong and smooth.
Ready to Purchase?
10. ACDelco Professional 9748UU Spark Plug Wire, Pack of 8

The ACDelco Professional 9748UU Spark Plug Wire is a pack of 8 wires made for strong spark delivery. Its wire conductor, length, and diameter ensure top protection and performance.
Spark plug distributor boot shapes and materials create a tight seal that is waterproof. Terminal designs hold plugs firmly and resist rust during setup.
Get this wire set today. It meets high quality standards. Install it for better engine life.
| Pros | Cons |
|---|---|
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Perfect For:
Need new spark plug wires? The ACDelco Professional 9748UU Spark Plug Wire set is for you! This reliable, high-quality set ensures a perfect fit, easy installation, and maximum spark delivery.
Ready to Purchase?
Buying Guide
Need new spark plug wires for your Escalade? Get ready for better engine power. The right set can save you money.
Many Escalade owners have seen big improvements. They report smoother rides and better fuel use.
Here’s what to think about before you buy!
Factors to Consider When Buying Spark Plug Wires:
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Compatibility: Make sure the set fits your Cadillac Escalade’s year (1999-2018) and engine type. Check product descriptions and part numbers carefully. This prevents fit issues and performance problems.
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Material Quality: Look for wires made with high-quality, heat-resistant materials like silicone or EPDM. This can prevent cracking and breakdown over time. Wires must handle engine heat for long time.
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Resistance: Lower resistance means more spark power reaches the plugs. This results in more complete burn in the cylinders This equals better engine performance and MPG. Check the specs before you purchase.
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Installation: Some kits are easier to install than others. Consider your skill level and look for sets with clear instructions. Direct-fit replacements make the job simple.
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Spark Plugs Included: Some sets include spark plugs. Replacing both plugs and wires at the same time can improve overall engine performance. It saves you labor and time.
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Brand Reputation & Warranty: Choose brands with good reviews and warranties. A warranty gives you peace of mind. You know the manufacturer stands behind its product.
Follow those steps. It helps you pick the perfect spark plug wire set. Get ready for a smooth, powerful Cadillac Escalade.